Publications

Publications made with imaging support from NMI.

2022

Nordenström M, Benselfelt T, Hollertz R, …, Söderberg D, Wågberg L, “The structure of cellulose nanofibril networks at low concentrations and their stabilizing action on colloidal particles.”, Carbohydr Polym, 2022, 297, 120046, https://doi.org/10.1016/j.carbpol.2022.120046

Crescitelli R, Filges S, Karimi N, …, Lässer C, Olofsson Bagge R, “Extracellular vesicle DNA from human melanoma tissues contains cancer-specific mutations.”, Front Cell Dev Biol, 2022, 10, 1028854, https://doi.org/10.3389/fcell.2022.1028854

Moffitt JR, Lundberg E, Heyn H, “The emerging landscape of spatial profiling technologies.”, Nat. Rev. Genet., 2022, 23 (12), 741-759, https://doi.org/10.1038/s41576-022-00515-3

Bonilla JC, Sørensen JL, Warming AS, Clausen MP, “Quantitative image analysis of protein foam microstructure and its correlation with rheological properties: Egg white foam”, Food Hydrocolloids, 2022, 133, 108010, https://doi.org/10.1016/j.foodhyd.2022.108010

Tonge JJ, Notley SV, Dunning MJ, …, Panoutsos G, Gad AKB, “Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo.”, Sci Rep, 2022, 12 (1), 19835, https://doi.org/10.1038/s41598-022-21952-4

Forsberg KM, Graffmo KS, Stenvall E, …, Brännström T, Andersen PM, “Widespread CNS pathology in amyotrophic lateral sclerosis homozygous for the D90A SOD1 mutation”, Acta Neuropathol, 2022, https://doi.org/10.1007/s00401-022-02519-z

Leyhr J, Waldmann L, Filipek-Górniok B, …, Allalou A, Haitina T, “A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint.”, Elife, 2022, 11, https://doi.org/10.7554/eLife.75749

Maurya DK, Berghard A, Bohm S, “A multivesicular body-like organelle mediates stimulus-regulated trafficking of olfactory ciliary transduction proteins.”, Nat Commun, 2022, 13 (1), 6889, https://doi.org/10.1038/s41467-022-34604-y

Schneider KL, Ahmadpour D, Keuenhof KS, …, Nyström T, Widlund PO, “Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates.”, J. Biol. Chem., 2022, 298 (11), 102476, https://doi.org/10.1016/j.jbc.2022.102476

Gineste C, Youhanna S, Vorrink SU, …, Lauschke VM, Westerblad H, “Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control”, iScience, 2022, 105654, https://doi.org/10.1016/j.isci.2022.105654

Michno W, Koutarapu S, Camacho R, …, Lashley T, Hanrieder J, “Chemical traits of cerebral amyloid angiopathy in familial British‐, Danish‐, and non‐Alzheimer ʼs dementias”, J. Neurochem., 2022, 163 (3), 233-246, https://doi.org/10.1111/jnc.15694

Schlegel J, Porebski B, Andronico L, …, Fernandez-Capetillo O, Sezgin E, “A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens”,, 2022, https://doi.org/10.1101/2022.10.10.511545

Koutarapu S, Ge J, Jha D, …, Michno W, Hanrieder J, “Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer’s Disease.”, Brain Connect, 2022, https://doi.org/10.1089/brain.2022.0047

Iribarren C, Nordlander S, Sundin J, …, Simrén M, Öhman L, “Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of colonoids.”, Neurogastroenterol. Motil., 2022, 34 (10), e14390, https://doi.org/10.1111/nmo.14390

Dolan B, Ermund A, Martinez-Abad B, Johansson MEV, Hansson GC, “Clearance of small intestinal crypts involves goblet cell mucus secretion by intracellular granule rupture and enterocyte ion transport.”, Sci Signal, 2022, 15 (752), eabl5848, https://doi.org/10.1126/scisignal.abl5848

Ruiz M, Svensk E, Einarsson E, Grahn EP, Pilon M, “A small molecule screen for paqr-2 suppressors identifies Tyloxapol as a membrane fluidizer for C. elegans and mammalian cells.”, Biochimica et Biophysica Acta (BBA) – Biomembranes, 2022, 1864 (9), 183959, https://doi.org/10.1016/j.bbamem.2022.183959

Waldmann L, Leyhr J, Zhang H, …, Öhman-Mägi C, Haitina T, “The role of Gdf5 in the development of the zebrafish fin endoskeleton.”, Dev. Dyn., 2022, 251 (9), 1535-1549, https://doi.org/10.1002/dvdy.399

Song J, Nilsson G, Xu Y, …, Zhu C, Wang X, “Temporal brain transcriptome analysis reveals key pathological events after germinal matrix hemorrhage in neonatal rats.”, J. Cereb. Blood Flow Metab., 2022, 42 (9), 1632-1649, https://doi.org/10.1177/0271678X221098811

Ragaller F, Andronico L, Sykora J, …, Vattulainen I, Sezgin E, “Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties.”, Open Biol, 2022, 12 (9), 220175, https://doi.org/10.1098/rsob.220175

Bekkhus T, Avenel C, Hanna S, …, Wählby C, Ulvmar MH, “Automated detection of vascular remodeling in tumor-draining lymph nodes by the deep-learning tool HEV-finder.”, J. Pathol., 2022, 258 (1), 4-11, https://doi.org/10.1002/path.5981

Raykova D, Kermpatsou D, Malmqvist T, …, Kampf C, Söderberg O, “A method for Boolean analysis of protein interactions at a molecular level.”, Nat Commun, 2022, 13 (1), 4755, https://doi.org/10.1038/s41467-022-32395-w

Gupta A, Sabirsh A, Wahlby C, Sintorn I, “SimSearch: A Human-in-The-Loop Learning Framework for Fast Detection of Regions of Interest in Microscopy Images.”, IEEE J Biomed Health Inform, 2022, 26 (8), 4079-4089, https://doi.org/10.1109/JBHI.2022.3177602

Mund A, Coscia F, Kriston A, …, Horvath P, Mann M, “Deep Visual Proteomics defines single-cell identity and heterogeneity.”, Nat. Biotechnol., 2022, 40 (8), 1231-1240, https://doi.org/10.1038/s41587-022-01302-5

Marco Salas S, Yuan X, Sylven C, …, Wählby C, Partel G, “De novo spatiotemporal modelling of cell-type signatures in the developmental human heart using graph convolutional neural networks.”, PLoS Comput. Biol., 2022, 18 (8), e1010366, https://doi.org/10.1371/journal.pcbi.1010366

Haase R, Fazeli E, Legland D, …, Klemm A, Tischer C, “A Hitchhiker’s guide through the bio-image analysis software universe.”, FEBS Lett., 2022, https://doi.org/10.1002/1873-3468.14451

Stenberg S, Li J, Gjuvsland AB, …, Omholt SW, Warringer J, “Genetically controlled mtDNA deletions prevent ROS damage by arresting oxidative phosphorylation.”, Elife, 2022, 11, https://doi.org/10.7554/eLife.76095

Banerjee D, Nayakawde NB, Antony D, …, Ul Haq U, Olausson M, “Characterization of Decellularized Implants for Extracellular Matrix Integrity and Immune Response Elicitation.”, Tissue Eng Part A, 2022, 28 (13-14), 621-639, https://doi.org/10.1089/ten.TEA.2021.0146

Kouznetsova A, Liu JG, Valentiniene S, Brismar H, Höög C, “Age‐dependent aneuploidy in mammalian oocytes instigated at the second meiotic division”, Aging Cell, 2022, 21 (7), https://doi.org/10.1111/acel.13649

Zhu X, Xie X, Das H, …, Hällberg BM, Falkenberg M, “Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.”, Cell, 2022, 185 (13), 2309-2323.e24, https://doi.org/10.1016/j.cell.2022.05.006

Arnold H, Panara V, Hußmann M, …, Schulte-Merker S, Koltowska K, “mafba and mafbb differentially regulate lymphatic endothelial cell migration in topographically distinct manners.”, Cell Rep, 2022, 39 (12), 110982, https://doi.org/10.1016/j.celrep.2022.110982

Verhoeven BM, Mei S, Olsen TK, …, Johnsen JI, Baryawno N, “The immune cell atlas of human neuroblastoma”, Cell Reports Medicine, 2022, 3 (6), 100657, https://doi.org/10.1016/j.xcrm.2022.100657

Hübner B, von Otter E, Ahsan B, …, Ludwig A, Sandin S, “Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy.”, Nucleic Acids Res., 2022, 50 (9), 5047-5063, https://doi.org/10.1093/nar/gkac309

Larsson S, Kettunen P, Carén H, “Orthotopic Transplantation of Human Paediatric High-Grade Glioma in Zebrafish Larvae.”, Brain Sci, 2022, 12 (5), https://doi.org/10.3390/brainsci12050625

Elebring E, Wallenius V, Casselbrant A, …, Marschall HU, Fändriks L, “A Fatty Diet Induces a Jejunal Ketogenesis Which Inhibits Local SGLT1-Based Glucose Transport via an Acetylation Mechanism-Results from a Randomized Cross-Over Study between Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy Volunteers.”, Nutrients, 2022, 14 (9), https://doi.org/10.3390/nu14091961

Julner A, Abbasi M, Menéndez-Benito V, “The microtubule plus-end tracking protein Bik1 is required for chromosome congression.”, Mol. Biol. Cell, 2022, 33 (5), br7, https://doi.org/10.1091/mbc.E21-10-0500

Bradley F, Franzén Boger M, Kaldhusdal V, …, Tjernlund A, Broliden K, “Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate.”, PLoS Pathog., 2022, 18 (5), e1010494, https://doi.org/10.1371/journal.ppat.1010494

Ichioka Y, Derks J, Dahlén G, Berglundh T, Larsson L, “Mechanical removal of biofilm on titanium discs: An in vitro study.”, J. Biomed. Mater. Res. Part B Appl. Biomater., 2022, 110 (5), 1044-1055, https://doi.org/10.1002/jbm.b.34978

Nair S, Leverin AL, Rocha-Ferreira E, …, Mallard C, Hagberg H, “Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia-Ischemia.”, Cells, 2022, 11 (7), https://doi.org/10.3390/cells11071193

Hallberg I, Persson S, Olovsson M, …, Rüegg J, Sjunnesson YCB, “Bovine oocyte exposure to perfluorohexane sulfonate (PFHxS) induces phenotypic, transcriptomic, and DNA methylation changes in resulting embryos in vitro.”, Reprod Toxicol, 2022, 109, 19-30, https://doi.org/10.1016/j.reprotox.2022.02.004

Kaimal JM, Tampere M, Le TH, …, Östling P, Stadler C, “Subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing”,, 2022, https://doi.org/10.1101/2022.03.29.482838

Cuéllar J, Vallin J, Svanström A, …, Valpuesta JM, Grantham J, “The Molecular Chaperone CCT Sequesters Gelsolin and Protects it from Cleavage by Caspase-3.”, J. Mol. Biol., 2022, 434 (5), 167399, https://doi.org/10.1016/j.jmb.2021.167399

Brodin ATS, Gabulya S, Wellfelt K, Karlsson TE, “Five Hours Total Sleep Deprivation Does Not Affect CA1 Dendritic Length or Spine Density.”, Front. Synaptic Neurosci., 2022, 14, 854160, https://doi.org/10.3389/fnsyn.2022.854160

Schmied L, Luu TT, Søndergaard JN, …, Saeed MB, Höglund P, “Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse”,, 2022, https://doi.org/10.1101/2022.03.08.483415

Stenudd M, Sabelström H, Llorens-Bobadilla E, …, Barnabé-Heider F, Frisén J, “Identification of a discrete subpopulation of spinal cord ependymal cells with neural stem cell properties.”, Cell Rep, 2022, 38 (9), 110440, https://doi.org/10.1016/j.celrep.2022.110440

Kay E, Stulz R, Becquart C, …, Andersson S, Kurczy M, “NanoSIMS Imaging Reveals the Impact of Ligand-ASO Conjugate Stability on ASO Subcellular Distribution”, Pharmaceutics, 2022, 14 (2), 463, https://doi.org/10.3390/pharmaceutics14020463

Nadeem A, Berg A, Pace H, …, Uhlin BE, Wai SN, “Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae.”, Elife, 2022, 11, https://doi.org/10.7554/eLife.73439

Jalalvand E, Alvelid J, Coceano G, …, Grillner S, Testa I, “ExSTED microscopy reveals contrasting functions of dopamine and somatostatin CSF-c neurons along the lamprey central canal.”, Elife, 2022, 11, https://doi.org/10.7554/eLife.73114

Michno W, Wehrli PM, Koutarapu S, …, Hopf C, Hanrieder J, “Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging.”, J. Neurochem., 2022, 160 (4), 482-498, https://doi.org/10.1111/jnc.15557

Aswendt M, Wilhelmsson U, Wieters F, …, Pekna M, Pekny M, “Reactive astrocytes prevent maladaptive plasticity after ischemic stroke.”, Prog Neurobiol, 2022, 209, 102199, https://doi.org/10.1016/j.pneurobio.2021.102199

Thomsen C, Malfatti E, Jovanovic A, …, Lindberg C, Oldfors A, “Proteomic characterisation of polyglucosan bodies in skeletal muscle in RBCK1 deficiency.”, Neuropathol Appl Neurobiol, 2022, 48 (1), e12761, https://doi.org/10.1111/nan.12761

Habicher J, Varshney GK, Waldmann L, …, Burgess SM, Ledin J, “Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development.”, PLoS Genet., 2022, 18 (2), e1010067, https://doi.org/10.1371/journal.pgen.1010067

Behanova A, Klemm A, Wählby C, “Spatial Statistics for Understanding Tissue Organization.”, Front Physiol, 2022, 13, 832417, https://doi.org/10.3389/fphys.2022.832417

Bäcklund FG, Schmuck B, Miranda GHB, …, Rydén J, Rising A, “An Image-Analysis-Based Method for the Prediction of Recombinant Protein Fiber Tensile Strength.”, Materials (Basel), 2022, 15 (3), https://doi.org/10.3390/ma15030708

Enrico A, Voulgaris D, Östmans R, …, Herland A, Stemme G, “3D Microvascularized Tissue Models by Laser-Based Cavitation Molding of Collagen.”, Adv Mater, 2022, e2109823, https://doi.org/10.1002/adma.202109823

Ekström K, Crescitelli R, Pétursson HI, …, Lässer C, Olofsson Bagge R, “Characterization of surface markers on extracellular vesicles isolated from lymphatic exudate from patients with breast cancer.”, BMC Cancer, 2022, 22 (1), 50, https://doi.org/10.1186/s12885-021-08870-w

Stoltenborg I, Peris-Sampedro F, Schéle E, …, Adan RAH, Dickson SL, “TRAPing Ghrelin-Activated Circuits: A Novel Tool to Identify, Target and Control Hormone-Responsive Populations in TRAP2 Mice.”, Int J Mol Sci, 2022, 23 (1), https://doi.org/10.3390/ijms23010559

Butt L, Unnersjö-Jess D, Höhne M, …, Schermer B, Benzing T, “Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease.”, J. Am. Soc. Nephrol., 2022, 33 (1), 138-154, https://doi.org/10.1681/ASN.2020060858

Wang Y, Acs B, Robertson S, …, Hartman J, Rantalainen M, “Improved breast cancer histological grading using deep learning.”, Ann. Oncol., 2022, 33 (1), 89-98, https://doi.org/10.1016/j.annonc.2021.09.007

Klemm A, Miura K, “Batch Processing Methods in ImageJ”, Springer, 2022, 7-27, https://doi.org/10.1007/978-3-030-76394-7_2

Makasewicz K, Wennmalm S, Linse S, Sparr E, “Alfa-Synuclein-induced deformation of small unilamellar vesicles”, QRB Discovery, 2022, 3, https://doi.org/10.1017/qrd.2022.9

Mota A, Berezicki S, Wernersson E, Harbers L, Li-Wang X, Gradin K, Peuckert C, Crosetto N, Bienko M. “FRET-FISH probes chromatin compaction at individual genomic loci in single cells”. Nat Commun. 2022; 13(1):6680. https://doi.org/10.1038/s41467-022-34183-y

Enrico A, Voulgaris D, Östmans R, Sundaravadivel N, Moutaux L, Cordier A, Niklaus F, Herland A, Stemme G. “3D Microvascularized Tissue Models by Laser-Based Cavitation Molding of Collagen”. Adv Mater. 2022;34(11):e2109823. https://doi.org/10.1002/adma.202109823.

2021

Rabasco S, Nguyen TDK, Gu C, …, Phan NTN, Ewing AG, “Localization and Absolute Quantification of Dopamine in Discrete Intravesicular Compartments Using NanoSIMS Imaging.”, Int J Mol Sci, 2021, 23 (1), https://doi.org/10.3390/ijms23010160

Pozo-Rodrigálvarez A, Li Y, Stokowska A, …, Pekny M, Pekna M, “C3a Receptor Signaling Inhibits Neurodegeneration Induced by Neonatal Hypoxic-Ischemic Brain Injury.”, Front Immunol, 2021, 12, 768198, https://doi.org/10.3389/fimmu.2021.768198

Omrani A, de Vrind VAJ, Lodder B, …, Meye FJ, Adan RAH, “Identification of Novel Neurocircuitry Through Which Leptin Targets Multiple Inputs to the Dopamine System to Reduce Food Reward Seeking.”, Biol. Psychiatry, 2021, 90 (12), 843-852, https://doi.org/10.1016/j.biopsych.2021.02.017

Carravilla P, Dasgupta A, Zhurgenbayeva G, …, Sezgin E, Eggeling C, “Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.”, Biophysical Reports, 2021, 1 (2), None, https://doi.org/10.1016/j.bpr.2021.100023

Unnersjö-Jess D, Ramdedovic A, Höhne M, …, Schermer B, Benzing T, “Three-Dimensional Super-Resolved Imaging of Paraffin-Embedded Kidney Samples”, Kidney360, 2021, 10.34067/KID.0005882021, https://doi.org/10.34067/kid.0005882021

Barmpatsalou V, Dubbelboer IR, Rodler A, …, Pedersen BL, Bergström CAS, “Physiological properties, composition and structural profiling of porcine gastrointestinal mucus.”, Eur J Pharm Biopharm, 2021, 169, 156-167, https://doi.org/10.1016/j.ejpb.2021.10.008

Hallberg I, Persson S, Olovsson M, …, Rüegg J, Sjunnesson YCB, “Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model.”, Toxicology, 2021, 464, 153028, https://doi.org/10.1016/j.tox.2021.153028

Qin Y, Huttlin EL, Winsnes CF, …, Lundberg E, Ideker T, “A multi-scale map of cell structure fusing protein images and interactions.”, Nature, 2021, https://doi.org/10.1038/s41586-021-04115-9

Ichioka Y, Derks J, Dahlén G, Berglundh T, Larsson L, “In vitro evaluation of chemical decontamination of titanium discs.”, Sci Rep, 2021, 11 (1), 22753, https://doi.org/10.1038/s41598-021-02220-3

Hickey JW, Neumann EK, Radtke AJ, …, Kelleher NL, Saka SK, “Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging.”, Nat. Methods, 2021, https://doi.org/10.1038/s41592-021-01316-y

Rambaran MA, Gorzsás A, Holmboe M, Ohlin CA, “Polyoxoniobates as molecular building blocks in thin films.”, Dalton Trans, 2021, 50 (44), 16030-16038, https://doi.org/10.1039/d1dt03116c

van Husen LS, Katsori A, Meineke B, …, Schedin-Weiss S, Elsässer SJ, “Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids.”, ChemBioChem, 2021, 22 (22), 3208-3213, https://doi.org/10.1002/cbic.202100399

Ygberg S, Akkuratov EE, Howard RJ, …, Brismar H, Aperia A, “A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy.”, J. Biol. Chem., 2021, 101355, https://doi.org/10.1016/j.jbc.2021.101355

Morud J, Hardege I, Liu H, …, Zhang Y, Schafer WR, “Deorphanization of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning.”, Curr. Biol., 2021, 31 (19), 4282-4292.e6, https://doi.org/10.1016/j.cub.2021.07.036

Chelebian E, Avenel C, Kartasalo K, …, Lundeberg J, Wählby C, “Morphological Features Extracted by AI Associated with Spatial Transcriptomics in Prostate Cancer.”, Cancers (Basel), 2021, 13 (19), https://doi.org/10.3390/cancers13194837

Chebli J, Rahmati M, Lashley T, …, Zetterberg H, Abramsson A, “The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish.”, Sci Rep, 2021, 11 (1), 19115, https://doi.org/10.1038/s41598-021-98487-7

Thofte O, Bettoni S, Su Y, …, Blom AM, Riesbeck K, “Nontypeable Haemophilus influenzae P5 Binds Human C4b-Binding Protein, Promoting Serum Resistance.”, J. Immunol., 2021, 207 (6), 1566-1577, https://doi.org/10.4049/jimmunol.2100105

Peris-Sampedro F, Stoltenborg I, Le May MV, …, Adan RAH, Dickson SL, “Genetic deletion of the ghrelin receptor (GHSR) impairs growth and blunts endocrine response to fasting in Ghsr-IRES-Cre mice.”, Mol Metab, 2021, 51, 101223, https://doi.org/10.1016/j.molmet.2021.101223

Haniffa M, Taylor D, Linnarsson S, …, Webb S, Human Cell Atlas Developmental Biological Network, “A roadmap for the Human Developmental Cell Atlas.”, Nature, 2021, 597 (7875), 196-205, https://doi.org/10.1038/s41586-021-03620-1

Devkota R, Kaper D, Bodhicharla R, …, Borén J, Pilon M, “A genetic titration of membrane composition in Caenorhabditis elegans reveals its importance for multiple cellular and physiological traits.”, Genetics, 2021, 219 (1), https://doi.org/10.1093/genetics/iyab093

Waldmann L, Leyhr J, Zhang H, …, Allalou A, Haitina T, “The broad role of Nkx3.2 in the development of the zebrafish axial skeleton.”, PLoS ONE, 2021, 16 (8), e0255953, https://doi.org/10.1371/journal.pone.0255953

Yu Y, Gao Y, Winblad B, Tjernberg LO, Schedin-Weiss S, “A Super-Resolved View of the Alzheimer’s Disease-Related Amyloidogenic Pathway in Hippocampal Neurons.”, J. Alzheimers Dis., 2021, 83 (2), 833-852, https://doi.org/10.3233/JAD-215008

Bernhem K, Fontana JM, Svensson D, …, Brismar H, Aperia A, “Super-resolution microscopy reveals that Na+/K+-ATPase signaling protects against glucose-induced apoptosis by deactivating Bad.”, Cell Death Dis, 2021, 12 (8), 739, https://doi.org/10.1038/s41419-021-04025-8

Dakhel S, Davies WIL, Joseph JV, …, Remeseiro S, Gunhaga L, “Chick fetal organ spheroids as a model to study development and disease.”, BMC Mol Cell Biol, 2021, 22 (1), 37, https://doi.org/10.1186/s12860-021-00374-6

Jiang M, Xie X, Zhu X, …, Larsson NG, Falkenberg M, “The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication.”, Sci Adv, 2021, 7 (27), https://doi.org/10.1126/sciadv.abf8631

Ehrencrona E, van der Post S, Gallego P, …, Hansson GC, Johansson MEV, “The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.”, J. Biol. Chem., 2021, 297 (1), 100871, https://doi.org/10.1016/j.jbc.2021.100871

Park KS, Svennerholm K, Crescitelli R, …, Gribonika I, Lötvall J, “Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy.”, J Extracell Vesicles, 2021, 10 (9), e12120, https://doi.org/10.1002/jev2.12120

Damenti M, Coceano G, Pennacchietti F, Bodén A, Testa I, “STED and parallelized RESOLFT optical nanoscopy of the tubular endoplasmic reticulum and its mitochondrial contacts in neuronal cells.”, Neurobiol. Dis., 2021, 155, 105361, https://doi.org/10.1016/j.nbd.2021.105361

Makasewicz K, Wennmalm S, Stenqvist B, …, Linse S, Sparr E, “Cooperativity of α-Synuclein Binding to Lipid Membranes.”, ACS Chem Neurosci, 2021, 12 (12), 2099-2109, https://doi.org/10.1021/acschemneuro.1c00006

Solorzano L, Wik L, Olsson Bontell T, …, Östman A, Wählby C, “Machine learning for cell classification and neighborhood analysis in glioma tissue.”, Cytometry A, 2021, https://doi.org/10.1002/cyto.a.24467

Michno W, Stringer KM, Enzlein T, …, Edwards FA, Hanrieder J, “Following spatial Aβ aggregation dynamics in evolving Alzheimer’s disease pathology by imaging stable isotope labeling kinetics.”, Sci Adv, 2021, 7 (25), https://doi.org/10.1126/sciadv.abg4855

Jabbar KS, Dolan B, Eklund L, …, Simren M, Hansson GC, “Association between Brachyspira and irritable bowel syndrome with diarrhoea.”, Gut, 2021, 70 (6), 1117-1129, https://doi.org/10.1136/gutjnl-2020-321466

Verron Q, Forslund E, Brandt L, …, Olofsson PE, Önfelt B, “NK cells integrate signals over large areas when building immune synapses but require local stimuli for degranulation.”, Sci Signal, 2021, 14 (684), eabe2740, https://doi.org/10.1126/scisignal.abe2740

Padma AM, Carrière L, Krokström Karlsson F, …, Brännström M, Hellström M, “Towards a bioengineered uterus: bioactive sheep uterus scaffolds are effectively recellularized by enzymatic preconditioning.”, NPJ Regen Med, 2021, 6 (1), 26, https://doi.org/10.1038/s41536-021-00136-0

Lundberg E, Funke J, Uhlmann V, …, Carpenter A, Coehlo LP, “Which image-based phenotypes are most promising for using AI to understand cellular functions and why?”, Cell Syst, 2021, 12 (5), 384-387, https://doi.org/10.1016/j.cels.2021.04.012

Östergren I, Pourrahimi AM, Darmadi I, …, Langhammer C, Müller C, “Highly Permeable Fluorinated Polymer Nanocomposites for Plasmonic Hydrogen Sensing.”, ACS Appl Mater Interfaces, 2021, 13 (18), 21724-21732, https://doi.org/10.1021/acsami.1c01968

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Crescitelli R, Lässer C, Jang SC, …, Olofsson Bagge R, Lötvall J, “Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation.”, J Extracell Vesicles, 2020, 9 (1), 1722433, https://doi.org/10.1080/20013078.2020.1722433

Liu Y, Liu Q, Krivoruchko A, Khoomrung S, Nielsen J, “Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production.”, Nat. Chem. Biol., 2020, 16 (2), 197-205, https://doi.org/10.1038/s41589-019-0431-2

Ström P, Kartasalo K, Olsson H, …, Egevad L, Eklund M, “Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study.”, Lancet Oncol, 2020, 21 (2), 222-232, https://doi.org/10.1016/S1470-2045(19)30738-7

Vallhov H, Johansson C, Veerman RE, Scheynius A, “Extracellular Vesicles Released From the Skin Commensal Yeast Malassezia sympodialis Activate Human Primary Keratinocytes.”, Front. Cell. Infect. Microbiol., 2020, 10, 6, https://doi.org/10.3389/fcimb.2020.00006

Deiana M, Chand K, Jamroskovic J, …, Chorell E, Sabouri N, “A Light-up Logic Platform for Selective Recognition of Parallel G-Quadruplex Structures via Disaggregation-Induced Emission.”, Angew. Chem. Int. Ed. Engl., 2020, 59 (2), 896-902, https://doi.org/10.1002/anie.201912027

2019

Islam T, Gharibyan AL, Lee CC, Olofsson A, “Morphological analysis of Apolipoprotein E binding to Aβ Amyloid using a combination of Surface Plasmon Resonance, Immunogold Labeling and Scanning Electron Microscopy.”, BMC Biotechnol., 2019, 19 (1), 97, https://doi.org/10.1186/s12896-019-0589-4

Günaydın G, Edfeldt G, Garber DA, …, Tjernlund A, Broliden K, “Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa.”, Sci Rep, 2019, 9 (1), 18120, https://doi.org/10.1038/s41598-019-54493-4

Jang SC, Crescitelli R, Cvjetkovic A, …, Kalluri R, Lötvall J, “Mitochondrial protein enriched extracellular vesicles discovered in human melanoma tissues can be detected in patient plasma”, J Extracell Vesicles, 2019, 8 (1), 1635420, https://doi.org/10.1080/20013078.2019.1635420

Shelke GV, Yin Y, Jang SC, …, Nilsson JA, Lötvall J, “Endosomal signalling via exosome surface TGFβ-1”, J Extracell Vesicles, 2019, 8 (1), 1650458, https://doi.org/10.1080/20013078.2019.1650458

Gul N, Karlsson J, Tängemo C, …, Bergö MO, Lindahl P, “The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway”, Sci Rep, 2019, 9 (1), 14667, https://doi.org/10.1038/s41598-019-51205-w

van der Post S, Jabbar KS, Birchenough G, …, Johansson MEV, Hansson GC, “Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis.”, Gut, 2019, 68 (12), 2142-2151, https://doi.org/10.1136/gutjnl-2018-317571

Ferro L, Gojkovic Z, Muñoz R, Funk C, “Growth performance and nutrient removal of a Chlorella vulgaris-Rhizobium sp. co-culture during mixotrophic feed-batch cultivation in synthetic wastewater”, Algal Research, 2019, 44, 101690, https://doi.org/10.1016/j.algal.2019.101690

Schwarz A, Möller-Hackbarth K, Ebarasi L, …, Lal M, Patrakka J, “Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement”, Sci Rep, 2019, 9 (1), 8888, https://doi.org/10.1038/s41598-019-45303-y

Wessels B, Seyfferth C, Escamez S, …, Felten J, Tuominen H, “An AP2/ERF transcription factor ERF139 coordinates xylem cell expansion and secondary cell wall deposition.”, New Phytol., 2019, 224 (4), 1585-1599, https://doi.org/10.1111/nph.15960

Uhlén M, Karlsson MJ, Hober A, …, Fagerberg L, Sivertsson Å, “The human secretome”, Sci. Signal., 2019, 12 (609), eaaz0274, https://doi.org/10.1126/scisignal.aaz0274

Joshi RN, Stadler C, Lehmann R, …, Schmidt A, Vesterlund M, “TcellSubC: An Atlas of the Subcellular Proteome of Human T Cells.”, Front Immunol, 2019, 10, 2708, https://doi.org/10.3389/fimmu.2019.02708

Nyström EEL, Arike L, Ehrencrona E, Hansson GC, Johansson MEV, “Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties.”, J. Biol. Chem., 2019, 294 (45), 17075-17089, https://doi.org/10.1074/jbc.RA119.009940

Volk JK, Nyström EEL, van der Post S, …, Hansson GC, Birchenough GMH, “The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.”, J. Exp. Med., 2019, 216 (11), 2602-2618, https://doi.org/10.1084/jem.20190679

Ossinger A, Bajic A, Pan S, …, Hailer NP, Schizas N, “A rapid and accurate method to quantify neurite outgrowth from cell and tissue cultures: Two image analytic approaches using adaptive thresholds or machine learning”, Journal of Neuroscience Methods, 2019, 331, 108522, https://doi.org/10.1016/j.jneumeth.2019.108522

Anderson K, Nilsson T, Fernandez‐Rodriguez J, “Challenges for CLEM from a Light Microscopy Perspective”, John Wiley & Sons Ltd, 2019, 2, 23-35, https://doi.org/10.1002/9781119086420.ch2

Fleming CL, Sandoz PA, Inghardt T, …, Grøtli M, Andréasson J, “A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding.”, Angew. Chem. Int. Ed. Engl., 2019, 58 (42), 15000-15004, https://doi.org/10.1002/anie.201909536

Wang Y, Wang C, Ranefall P, …, Tian L, Yu G, “SynQuant: an automatic tool to quantify synapses from microscopy images”, Bioinformatics, 2019, 36 (5), 1599-1606, https://doi.org/10.1093/bioinformatics/btz760

Rodrigues L, Schneider F, Zhang X, …, Lundmark R, Hubert M, “Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries.”, Journal of Colloid and Interface Science, 2019, 553, 820-833, https://doi.org/10.1016/j.jcis.2019.06.045

Fu Y, Jussi J, Wang Q, …, Yang X, Chen Y, “Endocytic pathway of vascular cell adhesion molecule 1 in human umbilical vein endothelial cell identified in vitro by using functionalized nontoxic fluorescent quantum dots”, Sensors and Actuators B: Chemical, 2019, 297, 126702, https://doi.org/10.1016/j.snb.2019.126702

Yau WL, Nguyen-Dinh V, Larsson E, …, Överby AK, Lundmark R, “Model System for the Formation of Tick-Borne Encephalitis Virus Replication Compartments without Viral RNA Replication.”, J. Virol., 2019, 93 (18), https://doi.org/10.1128/JVI.00292-19

Wilhelmsson U, Lebkuechner I, Leke R, …, Pekna M, Pekny M, “Nestin Regulates Neurogenesis in Mice Through Notch Signaling From Astrocytes to Neural Stem Cells.”, Cereb. Cortex, 2019, 29 (10), 4050-4066, https://doi.org/10.1093/cercor/bhy284

Wurm CA, Schwarz H, Jans DC, …, Humbel BM, Jakobs S, “Correlative STED super-resolution light and electron microscopy on resin sections”, J. Phys. D: Appl. Phys., 2019, 52 (37), 374003, https://doi.org/10.1088/1361-6463/ab2b31

de Pablo Y, Marasek P, Pozo-Rodrigálvarez A, …, Pekna M, Pekny M, “Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes.”, Cells, 2019, 8 (9), 1016, https://doi.org/10.3390/cells8091016

Hu M, Zhang Y, Guo X, …, Shao LR, Billig H, “Perturbed ovarian and uterine glucocorticoid receptor signaling accompanies the balanced regulation of mitochondrial function and NFκB-mediated inflammation under conditions of hyperandrogenism and insulin resistance.”, Life Sciences, 2019, 232, 116681, https://doi.org/10.1016/j.lfs.2019.116681

Lázaro-Ibáñez E, Lässer C, Shelke GV, …, García-Rodríguez A, Lötvall J, “DNA analysis of low- and high-density fractions defines heterogeneous subpopulations of small extracellular vesicles based on their DNA cargo and topology.”, J Extracell Vesicles, 2019, 8 (1), 1656993, https://doi.org/10.1080/20013078.2019.1656993

Schneider H, Berger E, Dolan B, …, Pelaseyed T, Hansson GC, “The human transmembrane mucin MUC17 responds to TNFα by increased presentation at the plasma membrane.”, Biochem. J., 2019, 476 (16), 2281-2295, https://doi.org/10.1042/BCJ20190180

Babazadeh R, Ahmadpour D, Jia S, …, Liu B, Nystrom T, “Syntaxin 5 Is Required for the Formation and Clearance of Protein Inclusions during Proteostatic Stress.”, Cell Rep, 2019, 28 (8), 2096-2110.e8, https://doi.org/10.1016/j.celrep.2019.07.053

Park KS, Svennerholm K, Shelke GV, …, Gribonika I, Lötvall J, “Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10.”, Stem Cell Res Ther, 2019, 10 (1), 231, https://doi.org/10.1186/s13287-019-1352-4

Kouznetsova A, Kitajima TS, Brismar H, Höög C, “Post-metaphase correction of aberrant kinetochore-microtubule attachments in mammalian eggs.”, EMBO Rep., 2019, 20 (8), e47905, https://doi.org/10.15252/embr.201947905

Lammel T, Wassmur B, Mackevica A, Chen CL, Sturve J, “Mixture toxicity effects and uptake of titanium dioxide (TiO 2) nanoparticles and 3,3′,4,4′-tetrachlorobiphenyl (PCB77) in juvenile brown trout following co-exposure via the diet.”, Aquat. Toxicol., 2019, 213, 105195, https://doi.org/10.1016/j.aquatox.2019.04.021

Wagner K, Häggström G, Skoglund N, …, Öhman M, Hofbauer H, “Layer formation mechanism of K-feldspar in bubbling fluidized bed combustion of phosphorus-lean and phosphorus-rich residual biomass”, Applied Energy, 2019, 248, 545-554, https://doi.org/10.1016/j.apenergy.2019.04.112

Siadat M, Aghazadeh N, Akbarifard F, Brismar H, Oktem O, “Joint Image Deconvolution and Separation Using Mixed Dictionaries.”, IEEE Trans. on Image Process., 2019, 28 (8), 3936-3945, https://doi.org/10.1109/TIP.2019.2903316

Gudmundsson S, Wilbe M, Filipek-Górniok B, …, Annerén G, Bondeson M, “TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish.”, Sci Rep, 2019, 9 (1), 10730, https://doi.org/10.1038/s41598-019-46632-8

Ranade SS, Delhomme N, García-Gil MR, “Global gene expression analysis in etiolated and de-etiolated seedlings in conifers.”, PLoS ONE, 2019, 14 (7), e0219272, https://doi.org/10.1371/journal.pone.0219272

Laraia L, Friese A, Corkery DP, …, Wu YW, Waldmann H, “The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis.”, Nat. Chem. Biol., 2019, 15 (7), 710-720, https://doi.org/10.1038/s41589-019-0307-5

Sen BC, Wasserstrom S, Findlay K, …, von Wachenfeldt C, Flärdh K, “Specific amino acid substitutions in β strand S2 of FtsZ cause spiraling septation and impair assembly cooperativity in Streptomyces spp.”, Mol. Microbiol., 2019, 112 (1), 184-198, https://doi.org/10.1111/mmi.14262

Wang W, Zhang X, Niittylä T, “OPENER Is a Nuclear Envelope and Mitochondria Localized Protein Required for Cell Cycle Progression in Arabidopsis.”, Plant Cell, 2019, 31 (7), 1446-1465, https://doi.org/10.1105/tpc.19.00033

Bengtsson E, Ranefall P, “Image Analysis in Digital Pathology: Combining Automated Assessment of Ki67 Staining Quality with Calculation of Ki67 Cell Proliferation Index.”, Cytometry A, 2019, 95 (7), 714-716, https://doi.org/10.1002/cyto.a.23685

Mottahedin A, Joakim Ek C, Truvé K, Hagberg H, Mallard C, “Choroid plexus transcriptome and ultrastructure analysis reveals a TLR2-specific chemotaxis signature and cytoskeleton remodeling in leukocyte trafficking.”, Brain, Behavior, and Immunity, 2019, 79, 216-227, https://doi.org/10.1016/j.bbi.2019.02.004

Wiel C, Le Gal K, Ibrahim MX, …, Sayin VI, Bergo MO, “BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis”, Cell, 2019, 178 (2), 330-345.e22, https://doi.org/10.1016/j.cell.2019.06.005

Boge L, Browning KL, Nordström R, …, Ringstad L, Andersson M, “Peptide-Loaded Cubosomes Functioning as an Antimicrobial Unit against Escherichia coli.”, ACS Appl Mater Interfaces, 2019, 11 (24), 21314-21322, https://doi.org/10.1021/acsami.9b01826

Panizza E, Zhang L, Fontana JM, …, Lehtiö J, Aperia A, “Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na+, K+–ATPase control of cell adhesion, proliferation, and survival”, The FASEB Journal, 2019, fj.201900445R, https://doi.org/10.1096/fj.201900445r

Klemm AH, Thomae AW, Wachal K, Dietzel S, “Tracking Microscope Performance: A Workflow to Compare Point Spread Function Evaluations Over Time.”, Microsc Microanal, 2019, 25 (3), 699-704, https://doi.org/10.1017/S1431927619000060

Nair S, Sobotka KS, Joshi P, …, Mallard C, Hagberg H, “Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo.”, Glia, 2019, 67 (6), 1047-1061, https://doi.org/10.1002/glia.23587

Malanga M, Seggio M, Kirejev V, …, Ericson MB, Sortino S, “A phototherapeutic fluorescent β-cyclodextrin branched polymer delivering nitric oxide.”, Biomater Sci, 2019, 7 (6), 2272-2276, https://doi.org/10.1039/c9bm00395a

Stoldt S, Stephan T, Jans DC, …, Hell SW, Jakobs S, “Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria.”, Proc. Natl. Acad. Sci. U.S.A., 2019, 116 (20), 9853-9858, https://doi.org/10.1073/pnas.1820364116

Nilsson LM, Zhang L, Bondar A, …, Scott L, Aperia A, “Prompt apoptotic response to high glucose in SGLT-expressing renal cells.”, Am. J. Physiol. Renal Physiol., 2019, 316 (5), F1078-F1089, https://doi.org/10.1152/ajprenal.00615.2018

Lundberg E, Borner GHH, “Spatial proteomics: a powerful discovery tool for cell biology.”, Nat Rev Mol Cell Biol, 2019, 20 (5), 285-302, https://doi.org/10.1038/s41580-018-0094-y

Maier DB, Diehl S, Bigler C, “Interannual variation in seasonal diatom sedimentation reveals the importance of late winter processes and their timing for sediment signal formation”, Limnol Oceanogr, 2019, 64 (3), 1186-1199, https://doi.org/10.1002/lno.11106

Lammel T, Mackevica A, Johansson BR, Sturve J, “Endocytosis, intracellular fate, accumulation, and agglomeration of titanium dioxide (TiO 2) nanoparticles in the rainbow trout liver cell line RTL-W1.”, Environ Sci Pollut Res, 2019, 26 (15), 15354-15372, https://doi.org/10.1007/s11356-019-04856-1

Ruiz M, Ståhlman M, Borén J, Pilon M, “AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.”, J. Lipid Res., 2019, 60 (5), 995-1004, https://doi.org/10.1194/jlr.M092494

Michno W, Nyström S, Wehrli P, …, Zetterberg H, Hanrieder J, “Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology.”, J. Biol. Chem., 2019, 294 (17), 6719-6732, https://doi.org/10.1074/jbc.RA118.006604

Kwong WL, Lee CC, Shchukarev A, Messinger J, “Cobalt-doped hematite thin films for electrocatalytic water oxidation in highly acidic media.”, Chem. Commun. (Camb.), 2019, 55 (34), 5017-5020, https://doi.org/10.1039/c9cc01369e

Johansson HJ, Socciarelli F, Vacanti NM, …, Børresen-Dale AL, Lehtiö J, “Breast cancer quantitative proteome and proteogenomic landscape.”, Nat Commun, 2019, 10 (1), 1600, https://doi.org/10.1038/s41467-019-09018-y

Peter B, Farge G, Pardo-Hernandez C, Tångefjord S, Falkenberg M, “Structural basis for adPEO-causing mutations in the mitochondrial TWINKLE helicase.”, Hum. Mol. Genet., 2019, 28 (7), 1090-1099, https://doi.org/10.1093/hmg/ddy415

Karras C, Smedh M, Förster R, …, Fernandez-Rodriguez J, Heintzmann R, “Successful optimization of reconstruction parameters in structured illumination microscopy – A practical guide”, Optics Communications, 2019, 436, 69-75, https://doi.org/10.1016/j.optcom.2018.12.005

Gupta A, Harrison PJ, Wieslander H, …, Sintorn I, Wählby C, “Deep Learning in Image Cytometry: A Review.”, Cytometry A, 2019, 95 (4), 366-380, https://doi.org/10.1002/cyto.a.23701

Suarez C, Piculell M, Modin O, …, Persson F, Hermansson M, “Thickness determines microbial community structure and function in nitrifying biofilms via deterministic assembly.”, Sci Rep, 2019, 9 (1), 5110, https://doi.org/10.1038/s41598-019-41542-1

Strandberg A, Skoglund N, Thyrel M, …, Broström M, Backman R, “Time-Resolved Study of Silicate Slag Formation During Combustion of Wheat Straw Pellets”, Energy Fuels, 2019, 33 (3), 2308-2318, https://doi.org/10.1021/acs.energyfuels.8b04294

Wu C, Klaesson A, Buskas J, …, Söderberg O, Wolf JBW, “In situ quantification of individual mRNA transcripts in melanocytes discloses gene regulation of relevance to speciation.”, J Exp Biol, 2019, 222 (Pt 5), jeb194431, https://doi.org/10.1242/jeb.194431

Fontana JM, Khodus GR, Unnersjö-Jess D, …, Aperia A, Brismar H, “Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney.”, FASEB J., 2019, 33 (3), 4089-4096, https://doi.org/10.1096/fj.201802054R

Yan H, Seignez C, Hjorth M, …, Phillipson M, Crouzier T, “Immune-informed mucin hydrogels evade fibrotic foreign body response in vivo”,, 2019, https://doi.org/10.1101/554865

Pettersson M, Pettersson J, Johansson A, Molin Thorén M, “Titanium release in peri-implantitis.”, J Oral Rehabil, 2019, 46 (2), 179-188, https://doi.org/10.1111/joor.12735

Corman A, Jung B, Häggblad M, …, Carreras-Puigvert J, Fernandez-Capetillo O, “A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats”, Cell Chem Biol, 2019, 26 (2), 235-243.e5, https://doi.org/10.1016/j.chembiol.2018.10.020

Moodie LWK, Hubert M, Zhou X, …, Wanrooij S, Hedberg C, “Photoactivated Colibactin Probes Induce Cellular DNA Damage.”, Angew. Chem. Int. Ed. Engl., 2019, 58 (5), 1417-1421, https://doi.org/10.1002/anie.201812326

Wang T, Zhang J, Hu M, …, Shao LR, Billig H, “Differential Expression Patterns of Glycolytic Enzymes and Mitochondria-Dependent Apoptosis in PCOS Patients with Endometrial Hyperplasia, an Early Hallmark of Endometrial Cancer, In Vivo and the Impact of Metformin In Vitro.”, Int. J. Biol. Sci., 2019, 15 (3), 714-725, https://doi.org/10.7150/ijbs.31425

Kozyatnyk I, Latham KG, Jansson S, “Valorization of Humic Acids by Hydrothermal Conversion into Carbonaceous Materials: Physical and Functional Properties”, ACS Sustainable Chem. Eng., 2019, 7 (2), 2585-2592, https://doi.org/10.1021/acssuschemeng.8b05614

Ahmad I, Karah N, Nadeem A, Wai SN, Uhlin BE, “Analysis of colony phase variation switch in Acinetobacter baumannii clinical isolates.”, PLoS ONE, 2019, 14 (1), e0210082, https://doi.org/10.1371/journal.pone.0210082

Fu Y, Jussi J, Elmlund L, …, Wang Q, Brismar H, “Intrinsic blinking characteristics of single colloidal CdSe-CdS/ZnS core-multishell quantum dots”, Phys. Rev. B, 2019, 99 (3), https://doi.org/10.1103/physrevb.99.035404

Lammel T, Thit A, Mouneyrac C, …, Sturve J, Selck H, “Trophic transfer of CuO NPs and dissolved Cu from sediment to worms to fish – a proof-of-concept study”, Environ. Sci.: Nano, 2019, 6 (4), 1140-1155, https://doi.org/10.1039/c9en00093c

2018

Ašmonaitė G, Sundh H, Asker N, Carney Almroth B, “Rainbow Trout Maintain Intestinal Transport and Barrier Functions Following Exposure to Polystyrene Microplastics.”, Environ. Sci. Technol., 2018, 52 (24), 14392-14401, https://doi.org/10.1021/acs.est.8b04848

Paulraj T, Wennmalm S, Riazanova AV, …, Crespo GA, Svagan AJ, “Porous Cellulose Nanofiber-Based Microcapsules for Biomolecular Sensing.”, ACS Appl Mater Interfaces, 2018, 10 (48), 41146-41154, https://doi.org/10.1021/acsami.8b16058

Ruiz M, Bodhicharla R, Svensk E, …, Boren J, Pilon M, “Membrane fluidity is regulated by the C. elegans transmembrane protein FLD-1 and its human homologs TLCD1/2.”, Elife, 2018, 7, https://doi.org/10.7554/eLife.40686

Johansson HJ, Vallhov H, Holm T, …, Lehtiö J, Scheynius A, “Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin”, Sci Rep, 2018, 8 (1), https://doi.org/10.1038/s41598-018-27451-9

Micaroni M, “Looking for a Treatment for Hailey-Hailey Disease: The Importance of Being Consistent in Case Reports.”, J Cutan Med Surg, 2018, 22 (6), 660, https://doi.org/10.1177/1203475418798021

Pudelko L, Edwards S, Balan M, …, Helleday T, Bräutigam L, “An orthotopic glioblastoma animal model suitable for high-throughput screenings.”, Neuro-oncology, 2018, 20 (11), 1475-1484, https://doi.org/10.1093/neuonc/noy071

Dusart P, Fagerberg L, Perisic L, …, Odeberg J, Butler LM, “A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein.”, Sci Rep, 2018, 8 (1), 14668, https://doi.org/10.1038/s41598-018-32859-4

Thomsen H, Graf FE, Farewell A, Ericson MB, “Exploring photoinactivation of microbial biofilms using laser scanning microscopy and confined 2-photon excitation.”, J. Biophotonics, 2018, 11 (10), e201800018, https://doi.org/10.1002/jbio.201800018

Sullivan DP, Winsnes CF, Åkesson L, …, Szantner A, Lundberg E, “Deep learning is combined with massive-scale citizen science to improve large-scale image classification.”, Nat. Biotechnol., 2018, 36 (9), 820-828, https://doi.org/10.1038/nbt.4225

Hofmeister W, Vaz R, Edwards S, Dueñas Rey A, Lindstrand A, “Loss of zebrafish ctnnd2b results in disorganised forebrain neuron clusters”,, 2018, https://doi.org/10.1101/420828

Fernández-Blanco JA, Fakih D, Arike L, …, Ermund A, Hansson GC, “Attached stratified mucus separates bacteria from the epithelial cells in COPD lungs.”, JCI Insight, 2018, 3 (17), https://doi.org/10.1172/jci.insight.120994

Echbarthi M, Vallin J, Grantham J, “Interactions between monomeric CCTδ and p150 Glued: A novel function for CCTδ at the cell periphery distinct from the protein folding activity of the molecular chaperone CCT.”, Exp. Cell Res., 2018, 370 (1), 137-149, https://doi.org/10.1016/j.yexcr.2018.06.018

Sütt S, Cansby E, Paul A, …, Enerbäck S, Mahlapuu M, “STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue.”, J Endocrinol, 2018, 238 (3), 187-202, https://doi.org/10.1530/JOE-18-0182

Bodhicharla R, Devkota R, Ruiz M, Pilon M, “Membrane Fluidity Is Regulated Cell Nonautonomously by Caenorhabditiselegans PAQR-2 and Its Mammalian Homolog AdipoR2.”, Genetics, 2018, 210 (1), 189-201, https://doi.org/10.1534/genetics.118.301272

Lizatović R, Assent M, Barendregt A, …, Wennmalm S, André I, “A Protein-Based Encapsulation System with Calcium-Controlled Cargo Loading and Detachment”, Angew. Chem. Int. Ed., 2018, 57 (35), 11334-11338, https://doi.org/10.1002/anie.201806466

Matuszewski DJ, Wählby C, Krona C, Nelander S, Sintorn IM, “Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma”, SLAS DISCOVERY: Advancing Life Sciences R&D, 2018, 247255521879141, https://doi.org/10.1177/2472555218791414

Karimi N, Cvjetkovic A, Jang SC, …, Lötvall J, Lässer C, “Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins”, Cell. Mol. Life Sci., 2018, 75 (15), 2873-2886, https://doi.org/10.1007/s00018-018-2773-4

Liebmann T, Fritz N, Kruusmägi M, …, Aperia A, Brismar H, “Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins”, Int J Mol Sci, 2018, 19 (8), 2214, https://doi.org/10.3390/ijms19082214

Mottram L, Liu J, Chavan S, …, Svennerholm AM, Holgersson J, “Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a glycans.”, Sci Rep, 2018, 8 (1), 11250, https://doi.org/10.1038/s41598-018-29258-0

Michno W, Kaya I, Nyström S, …, Zetterberg H, Hanrieder J, “Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism.”, Anal. Chem., 2018, 90 (13), 8130-8138, https://doi.org/10.1021/acs.analchem.8b01361

Gibbs A, Buggert M, Edfeldt G, …, Broliden K, Tjernlund A, “Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103-CD8+ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium.”, J. Infect. Dis., 2018, 218 (3), 453-465, https://doi.org/10.1093/infdis/jix661

Siwani S, França ASC, Mikulovic S, …, Tort ABL, Kullander K, “OLMα2 Cells Bidirectionally Modulate Learning”, Neuron, 2018, 99 (2), 404-412.e3, https://doi.org/10.1016/j.neuron.2018.06.022

Holzwarth K, Köhler R, Philipsen L, …, Niesner RA, Hauser AE, “Multiplexed fluorescence microscopy reveals heterogeneity among stromal cells in mouse bone marrow sections”, Cytometry, 2018, 93 (9), 876-888, https://doi.org/10.1002/cyto.a.23526

Chen M, Puschmann TB, Marasek P, …, Wilhelmsson U, Pekny M, “Increased Neuronal Differentiation of Neural Progenitor Cells Derived from Phosphovimentin-Deficient Mice.”, Mol Neurobiol, 2018, 55 (7), 5478-5489, https://doi.org/10.1007/s12035-017-0759-0

Nyström EEL, Birchenough GMH, van der Post S, …, Hansson GC, Johansson MEV, “Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity.”, EBioMedicine, 2018, 33, 134-143, https://doi.org/10.1016/j.ebiom.2018.05.031

Lammel T, Sturve J, “Assessment of titanium dioxide nanoparticle toxicity in the rainbow trout (Onchorynchus mykiss) liver and gill cell lines RTL-W1 and RTgill-W1 under particular consideration of nanoparticle stability and interference with fluorometric assays”, NanoImpact, 2018, 11, 1-19, https://doi.org/10.1016/j.impact.2018.01.001

Thomsen H, Marino N, Conoci S, Sortino S, Ericson MB, “Confined photo-release of nitric oxide with simultaneous two-photon fluorescence tracking in a cellular system.”, Sci Rep, 2018, 8 (1), 9753, https://doi.org/10.1038/s41598-018-27939-4

De Vadder F, Grasset E, Mannerås Holm L, …, Olofsson LE, Bäckhed F, “Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks.”, Proc. Natl. Acad. Sci. U.S.A., 2018, 115 (25), 6458-6463, https://doi.org/10.1073/pnas.1720017115

Gunasekera S, Fernandes-Cerqueira C, Wennmalm S, …, Jakobsson PJ, Göransson U, “Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis”, ACS Chem. Biol., 2018, 13 (6), 1525-1535, https://doi.org/10.1021/acschembio.8b00118

Spiess M, Hernandez-Varas P, Oddone A, …, Lakadamyali M, Strömblad S, “Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.”, J. Cell Biol., 2018, 217 (6), 1929-1940, https://doi.org/10.1083/jcb.201707075

Yu Y, Jans DC, Winblad B, Tjernberg LO, Schedin-Weiss S, “Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses”, Life Sci. Alliance, 2018, 1 (3), e201800028, https://doi.org/10.26508/lsa.201800028

Bram Ednersson S, Stenson M, Stern M, …, Hasselblom S, Andersson PO, “Expression of ribosomal and actin network proteins and immunochemotherapy resistance in diffuse large B cell lymphoma patients”, Br J Haematol, 2018, 181 (6), 770-781, https://doi.org/10.1111/bjh.15259

Nguyen DT, O’Hara M, Graneli C, …, Althage M, Heydarkhan-Hagvall S, “Humanizing Miniature Hearts through 4-Flow Cannulation Perfusion Decellularization and Recellularization.”, Sci Rep, 2018, 8 (1), 7458, https://doi.org/10.1038/s41598-018-25883-x

Lindström L, Li T, Malycheva D, …, Rosselló CA, Alvarado-Kristensson M, “The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization.”, Commun Biol, 2018, 1 (1), 37, https://doi.org/10.1038/s42003-018-0037-3

Hu M, Zhang Y, Feng J, …, Shao LR, Billig H, “Uterine progesterone signaling is a target for metformin therapy in PCOS-like rats.”, J Endocrinol, 2018, 237 (2), 123-137, https://doi.org/10.1530/JOE-18-0086

Wennmalm S, “Potentials and pitfalls of inverse fluorescence correlation spectroscopy”, Methods, 2018, 140-141, 23-31, https://doi.org/10.1016/j.ymeth.2018.01.005

Bernhem K, Blom H, Brismar H, “Quantification of endogenous and exogenous protein expressions of Na,K-ATPase with super-resolution PALM/STORM imaging.”, PLoS ONE, 2018, 13 (4), e0195825, https://doi.org/10.1371/journal.pone.0195825

Guala D, Bernhem K, Blal HA, …, Brismar H, Sonnhammer ELL, “Experimental validation of predicted cancer genes using FRET”, Methods Appl. Fluoresc., 2018, 6 (3), 035007, https://doi.org/10.1088/2050-6120/aab932

Trillo-Muyo S, Nilsson HE, Recktenwald CV, …, Hebert H, Hansson GC, “Granule-stored MUC5B mucins are packed by the non-covalent formation of N-terminal head-to-head tetramers.”, J. Biol. Chem., 2018, 293 (15), 5746-5754, https://doi.org/10.1074/jbc.RA117.001014

Werner T, Kumar R, Horvath I, Scheers N, Wittung-Stafshede P, “Abundant fish protein inhibits α-synuclein amyloid formation.”, Sci Rep, 2018, 8 (1), 5465, https://doi.org/10.1038/s41598-018-23850-0

Hofving T, Arvidsson Y, Almobarak B, …, Johanson V, Nilsson O, “The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines. Correction”, Endocr Relat Cancer, 2018, 25 (4), X1-X2, https://doi.org/10.1530/erc-17-0445e

Casselbrant A, Helander HF, “Effects of fixation on electrophysiology and structure of human jejunal villi.”, Microsc Res Tech, 2018, 81 (4), 376-383, https://doi.org/10.1002/jemt.22988

Unnersjö-Jess D, Scott L, Sevilla SZ, …, Blom H, Brismar H, “Confocal super-resolution imaging of the glomerular filtration barrier enabled by tissue expansion”, Kidney International, 2018, 93 (4), 1008-1013, https://doi.org/10.1016/j.kint.2017.09.019

Niu Z, Pontifex CS, Berini S, …, Pfeffer G, Milone M, “Myopathy With SQSTM1 and TIA1 Variants: Clinical and Pathological Features.”, Front Neurol, 2018, 9, 147, https://doi.org/10.3389/fneur.2018.00147

Mönnich M, Borgeskov L, Breslin L, …, Larsen LA, Pedersen LB, “CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium.”, Cell Rep, 2018, 22 (10), 2584-2592, https://doi.org/10.1016/j.celrep.2018.02.043

Agostinho A, Kouznetsova A, Hernández-Hernández A, …, Brismar H, Höög C, “Sexual dimorphism in the width of the mouse synaptonemal complex”, J Cell Sci, 2018, 131 (5), jcs212548, https://doi.org/10.1242/jcs.212548

Hofving T, Arvidsson Y, Almobarak B, …, Johanson V, Nilsson O, “The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.”, Endocr. Relat. Cancer, 2018, 25 (3), 367-380, https://doi.org/10.1530/ERC-17-0445

Wang X, Omar O, Vazirisani F, Thomsen P, Ekström K, “Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation.”, PLoS ONE, 2018, 13 (2), e0193059, https://doi.org/10.1371/journal.pone.0193059

Staaf E, Hedde PN, Bagawath Singh S, …, Gratton E, Johansson S, “Educated natural killer cells show dynamic movement of the activating receptor NKp46 and confinement of the inhibitory receptor Ly49A”, Sci. Signal., 2018, 11 (517), eaai9200, https://doi.org/10.1126/scisignal.aai9200

Zhang H, Ericsson M, Virtanen M, …, Vahlquist A, Törmä H, “Quantitative image analysis of protein expression and colocalisation in skin sections”, Exp Dermatol, 2018, 27 (2), 196-199, https://doi.org/10.1111/exd.13457

Schroeder BO, Birchenough GMH, Ståhlman M, …, Hansson GC, Bäckhed F, “Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration.”, Cell Host Microbe, 2018, 23 (1), 27-40.e7, https://doi.org/10.1016/j.chom.2017.11.004

Bernhem K, Brismar H, “SMLocalizer, a GPU accelerated ImageJ plugin for single molecule localization microscopy”, Bioinformatics, 2018, 34 (1), 137-138, https://doi.org/10.1093/bioinformatics/btx553

Lindström L, Alvarado-Kristensson M, “Characterization of gamma-tubulin filaments in mammalian cells.”, Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, 2018, 1865 (1), 158-171, https://doi.org/10.1016/j.bbamcr.2017.10.008

Solorzano L, Almeida GM, Mesquita B, …, Oliveira C, Wählby C, “Whole Slide Image Registration for the Study of Tumor Heterogeneity”,, 2018, 95-102, https://doi.org/10.1007/978-3-030-00949-6_12

2017

Boström J, Sramkova Z, Salašová A, …, Altun M, Andäng M, “Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells”, PLoS ONE, 2017, 12 (12), e0188772, https://doi.org/10.1371/journal.pone.0188772

Agholme L, Clarin M, Gkanatsiou E, …, Portelius E, Zetterberg H, “Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ.”, Molecular and Cellular Neuroscience, 2017, 85, 211-219, https://doi.org/10.1016/j.mcn.2017.10.009

Sadanandan SK, Ranefall P, Le Guyader S, Wählby C, “Automated Training of Deep Convolutional Neural Networks for Cell Segmentation”, Sci Rep, 2017, 7 (1), https://doi.org/10.1038/s41598-017-07599-6

Petersen J, Wright SC, Rodríguez D, …, Carlsson J, Schulte G, “Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling”, Nat Commun, 2017, 8 (1), https://doi.org/10.1038/s41467-017-00253-9

Carreras-Puigvert J, Zitnik M, Jemth AS, …, Zupan B, Helleday T, “A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family”, Nat Commun, 2017, 8 (1), https://doi.org/10.1038/s41467-017-01642-w

Matuszewski DJ, Hast A, Wählby C, Sintorn IM, “A short feature vector for image matching: The Log-Polar Magnitude feature descriptor.”, PLoS ONE, 2017, 12 (11), e0188496, https://doi.org/10.1371/journal.pone.0188496

Röhl M, Lajoie J, Tjernlund A, …, Fowke KR, Broliden K, “Highly HIV-exposed HIV uninfected Kenyan female sex workers display a thick ectocervical epithelium”, HIV&Hepatitis Nordic Conference, Stockholm, 2017-09-27-29, 2017

Bombrun M, Gao H, Ranefall P, …, Arner P, Wählby C, “Quantitative high-content/high-throughput microscopy analysis of lipid droplets in subject-specific adipogenesis models.”, Cytometry A, 2017, 91 (11), 1068-1077, https://doi.org/10.1002/cyto.a.23265

Ly T, Whigham A, Clarke R, …, Wadsworth P, Lamond AI, “Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS.”, Elife, 2017, 6, https://doi.org/10.7554/eLife.27574

Emmanouilidou A, Ranefall P, Bandaru M, …, Ingelsson E, den Hoed M, “Zebrafish larvae as a model system for high-throughput, image-based screens in diabetes and insulin resistance”, ASHG 2017 Annual Meeting – The American Society of Human Genetics, 2017

den Hoed M, Emmanouilidou A, Bandaru M, …, Larsson A, Ingelsson E, “Zebrafish larvae as a model system for high-throughput, image-based genetic screens in cardiometabolic diseases”, ASHG 2017 Annual Meeting – The American Society of Human Genetics, 2017

Bandaru M, Emmanouilidou A, Ranefall P, …, Ingelsson E, den Hoed M, “Large-scale validation of zebrafish larvae as a model system for genetic screens in dyslipidaemia, atherosclerosis and coronary artery disease”, ASHG 2017 Annual Meeting – The American Society of Human Genetics, 2017

von der Heyde B, Emmanouilidou A, Klingström T, …, Allalou A, den Hoed M, “Identifying and characterizing causal genes in GWAS-identified loci for heart rate variability using high-throughput, image-based screens in zebrafish larvae”, ASHG 2017 Annual Meeting – The American Society of Human Genetics, 2017, https://doi.org/10.1161/atvb.38.suppl_1.472

Pudelko L, Rouhi P, Sanjiv K, …, Helleday T, Bräutigam L, “Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.”, Oncotarget, 2017, 8 (49), 84671-84684, https://doi.org/10.18632/oncotarget.19404

Ribeiro D, Horvath I, Heath N, …, Forslöw A, Wittung-Stafshede P, “Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation.”, Proc. Natl. Acad. Sci. U.S.A., 2017, 114 (42), 11127-11132, https://doi.org/10.1073/pnas.1711389114

Thomsen H, Benkovics G, Fenyvesi É, …, Malanga M, Ericson MB, “Delivery of cyclodextrin polymers to bacterial biofilms – An exploratory study using rhodamine labelled cyclodextrins and multiphoton microscopy.”, Int J Pharm, 2017, 531 (2), 650-657, https://doi.org/10.1016/j.ijpharm.2017.06.011

Sadanandan SK, Karlsson J, Wahlby C, “Spheroid Segmentation Using Multiscale Deep Adversarial Networks”, The IEEE International Conference on Computer Vision (ICCV), 2017, 2017, 36-41, https://doi.org/10.1109/iccvw.2017.11

Edfeldt G, Lajoie J, Röhl M, Tjernlund A, “Hormonal contraceptive use affects HIV susceptibility: mechanisms revealed by image analysis”, Scand J Immunol, 2017, 86 (4), 249-350

Forslid G, Wieslander H, Bengtsson E, …, Stark CR, Sadanandan SK, “Deep Convolutional Neural Networks for Detecting Cellular Changes Due to Malignancy”, The IEEE International Conference on Computer Vision (ICCV), 2017, 2017, https://doi.org/10.1109/iccvw.2017.18

Sun JB, Holmgren J, Larena M, …, Bresnick AR, Xiang Z, “Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin.”, Front Immunol, 2017, 8, 1119, https://doi.org/10.3389/fimmu.2017.01119

Abrahamsson S, Blom H, Agostinho A, …, Heintzmann R, Brismar H, “Multifocus structured illumination microscopy for fast volumetric super-resolution imaging”, Biomed. Opt. Express, 2017, 8 (9), 4135, https://doi.org/10.1364/boe.8.004135

Devkota R, Svensk E, Ruiz M, …, Borén J, Pilon M, “The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids.”, PLoS Genet., 2017, 13 (9), e1007004, https://doi.org/10.1371/journal.pgen.1007004

Gliga AR, Edoff K, Caputo F, …, Ceccatelli S, Fadeel B, “Cerium oxide nanoparticles inhibit differentiation of neural stem cells.”, Sci Rep, 2017, 7 (1), 9284, https://doi.org/10.1038/s41598-017-09430-8

Fernandez-Rodriguez J, Nilsson T, “Membrane trafficking under the microscope, what new imaging technologies have brought to light”, CRC Press, 2017, 1st Edition

Svensson S, Trobos M, Omar O, Thomsen P, “Site-specific gene expression analysis of implant-near cells in a soft tissue infection model – Application of laser microdissection to study biomaterial-associated infection.”, J. Biomed. Mater. Res., 2017, 105 (8), 2210-2217, https://doi.org/10.1002/jbm.a.36088

Talebizadeh N, Hagström NZ, Yu Z, …, Söderberg P, Wählby C, “Objective automated quantification of fluorescence signal in histological sections of rat lens”, Cytometry, 2017, 91 (8), 815-821, https://doi.org/10.1002/cyto.a.23131

Liu W, Li H, Edin F, …, Pfaller K, Rask-Andersen H, “Molecular composition and distribution of gap junctions in the sensory epithelium of the human cochlea-a super-resolution structured illumination microscopy (SR-SIM) study.”, Ups. J. Med. Sci., 2017, 122 (3), 160-170, https://doi.org/10.1080/03009734.2017.1322645

Bao J, Huang M, Petranovic D, Nielsen J, “Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae.”, Appl. Environ. Microbiol., 2017, 83 (14), https://doi.org/10.1128/AEM.03400-16

Blom H, Widengren J, “Stimulated Emission Depletion Microscopy.”, Chem. Rev., 2017, 117 (11), 7377-7427, https://doi.org/10.1021/acs.chemrev.6b00653

Wilhelmsson U, Andersson D, de Pablo Y, …, Pekny M, Pekna M, “Injury Leads to the Appearance of Cells with Characteristics of Both Microglia and Astrocytes in Mouse and Human Brain.”, Cereb. Cortex, 2017, 27 (6), 3360-3377, https://doi.org/10.1093/cercor/bhx069

Thul PJ, Åkesson L, Wiking M, …, Uhlén M, Lundberg E, “A subcellular map of the human proteome.”, Science, 2017, 356 (6340), https://doi.org/10.1126/science.aal3321

Monterisi S, Lobo MJ, Livie C, …, Micaroni M, Zaccolo M, “PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling.”, Elife, 2017, 6, https://doi.org/10.7554/eLife.21374

Kaya I, Michno W, Brinet D, …, Zetterberg H, Hanrieder J, “Histology-Compatible MALDI Mass Spectrometry Based Imaging of Neuronal Lipids for Subsequent Immunofluorescent Staining.”, Anal. Chem., 2017, 89 (8), 4685-4694, https://doi.org/10.1021/acs.analchem.7b00313

Kaucka M, Zikmund T, Tesarova M, …, Fried K, Adameyko I, “Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage”, Elife, 2017, 6, https://doi.org/10.7554/elife.25902

Winsnes CF, Sullivan DP, Smith K, Lundberg E, “Multi-label prediction of subcellular localization in confocal images using deep neural networks”, Molecular Biology of the Cell, 2017, 27

Morán J, Stokowska A, Walker FR, …, Hagberg H, Pekna M, “Intranasal C3a treatment ameliorates cognitive impairment in a mouse model of neonatal hypoxic-ischemic brain injury.”, Exp. Neurol., 2017, 290, 74-84, https://doi.org/10.1016/j.expneurol.2017.01.001

Micaroni M, “Editorial for the special issue on “Golgi-related human disorders”.”, Tissue and Cell, 2017, 49 (2 Pt A), 131-132, https://doi.org/10.1016/j.tice.2017.03.004

Skjolding LM, Ašmonaitė G, Jølck RI, …, Baun A, Sturve J, “An assessment of the importance of exposure routes to the uptake and internal localisation of fluorescent nanoparticles in zebrafish (Danio rerio), using light sheet microscopy.”, Nanotoxicology, 2017, 11 (3), 351-359, https://doi.org/10.1080/17435390.2017.1306128

Bodvard K, Peeters K, Roger F, …, Käll M, Molin M, “Light-sensing via hydrogen peroxide and a peroxiredoxin.”, Nat Commun, 2017, 8 (1), 14791, https://doi.org/10.1038/ncomms14791

Vidal-Quadras M, Holst MR, Francis MK, …, Martín-Belmonte F, Lundmark R, “Endocytic turnover of Rab8 controls cell polarization.”, J. Cell. Sci., 2017, 130 (6), 1147-1157, https://doi.org/10.1242/jcs.195420

Borglin J, Selegård R, Aili D, Ericson MB, “Peptide Functionalized Gold Nanoparticles as a Stimuli Responsive Contrast Medium in Multiphoton Microscopy.”, Nano Lett., 2017, 17 (3), 2102-2108, https://doi.org/10.1021/acs.nanolett.7b00611

Birchenough GM, Dalgakiran F, Witcomb LA, …, Hansson GC, Taylor PW, “Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection.”, Sci Rep, 2017, 7 (1), 83, https://doi.org/10.1038/s41598-017-00123-w

Reuss M, Fördős F, Blom H, …, Högberg B, Brismar H, “Measuring true localization accuracy in super resolution microscopy with DNA-origami nanostructures”, New J. Phys., 2017, 19 (2), 025013, https://doi.org/10.1088/1367-2630/aa5f74

Alkasalias T, Alexeyenko A, Hennig K, …, Gad AK, Pavlova T, “RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.”, Proc. Natl. Acad. Sci. U.S.A., 2017, 114 (8), E1413-E1421, https://doi.org/10.1073/pnas.1621161114

Kaya I, Brinet D, Michno W, …, Blennow K, Hanrieder J, “Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer’s Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.”, ACS Chem Neurosci, 2017, 8 (2), 347-355, https://doi.org/10.1021/acschemneuro.6b00391

Risal S, Zhang J, Adhikari D, …, Kaldis P, Liu K, “MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in mice.”, Cell Discov, 2017, 3 (1), 16052, https://doi.org/10.1038/celldisc.2016.52

Stokowska A, Atkins AL, Morán J, …, Dragunow M, Pekna M, “Complement peptide C3a stimulates neural plasticity after experimental brain ischaemia.”, Brain, 2017, 140 (2), 353-369, https://doi.org/10.1093/brain/aww314

Blockhuys S, Wittung-Stafshede P, “Copper chaperone Atox1 plays role in breast cancer cell migration.”, Biochem. Biophys. Res. Commun., 2017, 483 (1), 301-304, https://doi.org/10.1016/j.bbrc.2016.12.148

Dolatabadi S, Candia J, Akrap N, …, Åman P, Ståhlberg A, “Cell Cycle and Cell Size Dependent Gene Expression Reveals Distinct Subpopulations at Single-Cell Level.”, Front Genet, 2017, 8, 1, https://doi.org/10.3389/fgene.2017.00001

Terriac E, Coceano G, Mavajian Z, …, Lautenschläger F, Gad A, “Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts”, Cells, 2017, 6 (1), 2, https://doi.org/10.3390/cells6010002

Skogs M, Stadler C, Schutten R, …, Uhlén M, Lundberg E, “Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.”, J. Proteome Res., 2017, 16 (1), 147-155, https://doi.org/10.1021/acs.jproteome.6b00821

Ishaq O, Sadanandan SK, Wählby C, “Deep Fish: Deep Learning–Based Classification of Zebrafish Deformation for High-Throughput Screening”, SLAS DISCOVERY: Advancing Life Sciences R&D, 2017, 22 (1), 102-107, https://doi.org/10.1177/1087057116667894

Schizas N, Perry S, Andersson B, …, Kullander K, Hailer NP, “Differential Neuroprotective Effects of Interleukin-1 Receptor Antagonist on Spinal Cord Neurons after Excitotoxic Injury”, Neuroimmunomodulation, 2017, 24 (4-5), 220-230, https://doi.org/10.1159/000484607

Bombrun M, Ranefall P, Lindblad J, …, Nilsson M, Wählby C, “Decoding Gene Expression in 2D and 3D”, Scandinavian Conference on Image Analysis 2017, 2017, 257-268, https://doi.org/10.1007/978-3-319-59129-2_22

2016

Villamil Giraldo AM, Fyrner T, Wennmalm S, …, Öllinger K, Ederth T, “Spontaneous Vesiculation and pH-Induced Disassembly of a Lysosomotropic Detergent: Impacts on Lysosomotropism and Lysosomal Delivery.”, Langmuir, 2016, 32 (50), 13566-13575, https://doi.org/10.1021/acs.langmuir.6b03458

Scharaw S, Iskar M, Ori A, …, Bork P, Pepperkok R, “The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.”, J. Cell Biol., 2016, 215 (4), 543-558, https://doi.org/10.1083/jcb.201601090

Gibbs A, Buggert M, Ranefall P, …, Broliden K, Tjernlund A, “Analysis of the Distribution of CD103 on CD8 T Cells in Blood and Genital Mucosa of HIVinfected Female Sex Workers”, Conference on HIV Research for Prevention (HIV R4P), 2016, October 17–20, Chicago, 2016

Blom H, Bernhem K, Brismar H, “Sodium pump organization in dendritic spines.”, Neurophotonics, 2016, 3 (4), 041803, https://doi.org/10.1117/1.NPh.3.4.041803

Nagaraj V, Kazim AS, Helgeson J, …, Zhang E, Renström E, “Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol.”, Mol. Endocrinol., 2016, 30 (10), 1059-1069, https://doi.org/10.1210/me.2016-1023

, “Abstracts of the HIV Research for Prevention Meeting, HIVR4P, 17-20 October, 2016, Chicago, USA”, AIDS Research and Human Retroviruses, 2016, 32 (S1), 1-409, https://doi.org/10.1089/aid.2016.5000.abstracts

Uhlen M, Bandrowski A, Carr S, …, Snyder M, Yamamoto T, “A proposal for validation of antibodies.”, Nat. Methods, 2016, 13 (10), 823-827, https://doi.org/10.1038/nmeth.3995

Nejedla M, Sadi S, Sulimenko V, …, Aspenström P, Karlsson R, “Profilin connects actin assembly with microtubule dynamics.”, Mol. Biol. Cell, 2016, 27 (15), 2381-2393, https://doi.org/10.1091/mbc.E15-11-0799

Kaucka M, Ivashkin E, Gyllborg D, …, Hellander A, Adameyko I, “Analysis of neural crest-derived clones reveals novel aspects of facial development.”, Sci Adv, 2016, 2 (8), e1600060, https://doi.org/10.1126/sciadv.1600060

Liu W, Edin F, Blom H, …, Laurell G, Rask-Andersen H, “Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man.”, Cell Tissue Res., 2016, 365 (1), 13-27, https://doi.org/10.1007/s00441-016-2359-0

Burlaka I, Nilsson LM, Scott L, …, Brismar H, Aperia A, “Prevention of apoptosis averts glomerular tubular disconnection and podocyte loss in proteinuric kidney disease.”, Kidney Int., 2016, 90 (1), 135-148, https://doi.org/10.1016/j.kint.2016.03.026

Agostinho A, Manneberg O, van Schendel R, …, Brismar H, Höög C, “High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation.”, EMBO Rep., 2016, 17 (6), 901-913, https://doi.org/10.15252/embr.201642030

Vanherberghen B, Frisk T, Forslund E, …, Guldevall K, Önfelt B, “Microwell-Based Live Cell Imaging of NK Cell Dynamics to Assess Heterogeneity in Motility and Cytotoxic Response.”, Methods Mol. Biol., 2016, 1441, 87-106, https://doi.org/10.1007/978-1-4939-3684-7_8

Guldevall K, Brandt L, Forslund E, …, Uhlin M, Önfelt B, “Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.”, Front Immunol, 2016, 7, 119, https://doi.org/10.3389/fimmu.2016.00119

Rabasovic MD, Sisamakis E, Wennmalm S, Widengren J, “Label-Free Fluctuation Spectroscopy Based on Coherent Anti-Stokes Raman Scattering from Bulk Water Molecules.”, Chemphyschem, 2016, 17 (7), 1025-1033, https://doi.org/10.1002/cphc.201501129

Aperia A, Akkuratov EE, Fontana JM, Brismar H, “Na+-K+-ATPase, a new class of plasma membrane receptors.”, Am. J. Physiol., Cell Physiol., 2016, 310 (7), C491-C495, https://doi.org/10.1152/ajpcell.00359.2015

Ranefall P, Wählby C, “Global gray-level thresholding based on object size.”, Cytometry A, 2016, 89 (4), 385-390, https://doi.org/10.1002/cyto.a.22806

Schedin-Weiss S, Caesar I, Winblad B, Blom H, Tjernberg LO, “Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse.”, Acta Neuropathol Commun, 2016, 4, 29, https://doi.org/10.1186/s40478-016-0296-5

Holm A, Magnusson KE, Vikström E, “Pseudomonas aeruginosa N-3-oxo-dodecanoyl-homoserine Lactone Elicits Changes in Cell Volume, Morphology, and AQP9 Characteristics in Macrophages”, Front. Cell. Infect. Microbiol., 2016, 6, https://doi.org/10.3389/fcimb.2016.00032

Matuszewski DJ, Wählby C, Puigvert JC, Sintorn IM, “PopulationProfiler: A Tool for Population Analysis and Visualization of Image-Based Cell Screening Data”, PLoS ONE, 2016, 11 (3), e0151554, https://doi.org/10.1371/journal.pone.0151554

Navarro JR, Wennmalm S, Godfrey J, Breitholtz M, Edlund U, “Luminescent Nanocellulose Platform: From Controlled Graft Block Copolymerization to Biomarker Sensing.”, Biomacromolecules, 2016, 17 (3), 1101-1109, https://doi.org/10.1021/acs.biomac.5b01716

Turdalieva A, Solandt J, Shambetova N, …, Zelenina M, Fu Y, “Bioelectric and Morphological Response of Liquid-Covered Human Airway Epithelial Calu-3 Cell Monolayer to Periodic Deposition of Colloidal 3-Mercaptopropionic-Acid Coated CdSe-CdS/ZnS Core-Multishell Quantum Dots.”, PLoS ONE, 2016, 11 (2), e0149915, https://doi.org/10.1371/journal.pone.0149915

Liu F, Koval M, Ranganathan S, …, Kelleher NL, Baker MS, “Systems Proteomics View of the Endogenous Human Claudin Protein Family.”, J. Proteome Res., 2016, 15 (2), 339-359, https://doi.org/10.1021/acs.jproteome.5b00769

Sadanandan SK, Baltekin O, Magnusson KEG, …, Elf J, Wahlby C, “Segmentation and Track-Analysis in Time-Lapse Imaging of Bacteria”, IEEE J. Sel. Top. Signal Process., 2016, 10 (1), 174-184, https://doi.org/10.1109/jstsp.2015.2491304

Unnersjö-Jess D, Scott L, Blom H, Brismar H, “Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue.”, Kidney Int., 2016, 89 (1), 243-247, https://doi.org/10.1038/ki.2015.308

Sadanandan SK, Ranefall P, Wählby C, “Feature Augmented Deep Neural Networks for Segmentation of Cells”,, 2016, 231-243, https://doi.org/10.1007/978-3-319-46604-0_17

Mignardi M, Ishaq O, Qian X, Wahlby C, “Bridging Histology and Bioinformatics—Computational Analysis of Spatially Resolved Transcriptomics”, Proc. IEEE, 2016, 1-12, https://doi.org/10.1109/jproc.2016.2538562